α-Lipoic Acid for Aging and Diabetes: The Benefits of Extending Plasma Half-Life
نویسنده
چکیده
In 1937, a component of potato extract, named “potato growth factor”, was discovered to be necessary for the growth of Lactobacillus (1). Subsequent work by a number of laboratories led to the isolation and purification of the active compound in 1951 (2). The compound was identified as α-lipoic acid (LA; formerly referred to as thioctic acid), an eight-carbon dithiol containing a single chiral center (Figure 1).
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تاریخ انتشار 2000